Coordination of MAPK and p53 dynamics in the cellular responses to DNA damage and oxidative stress

Abstract In response to different cellular stresses, the transcription factor p53 undergoes different dynamics. p53 dynamics, in turn, control cell fate. However, distinct stresses can generate the same p53 dynamics but different cell fate outcomes, suggesting integration of dynamic information from...

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Bibliographic Details

Published in:	Molecular Systems Biology
Main Authors:	Ryan L Hanson, Eric Batchelor
Format:	Article
Language:	English
Published:	Springer Nature 2022-12-01
Subjects:	cell stress responses dynamics MAPKs p53 single cells
Online Access:	https://doi.org/10.15252/msb.202211401