Cigarette smoke modulates vascular smooth muscle phenotype: implications for carotid and cerebrovascular disease.

The role of smooth muscle cell (SMC) phenotypic modulation in the cerebral circulation and pathogenesis of stroke has not been determined. Cigarette smoke is a major risk factor for atherosclerosis, but potential mechanisms are unclear, and its role in SMC phenotypic modulation has not been establis...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Robert M Starke, Muhammad S Ali, Pascal M Jabbour, Stavropoula I Tjoumakaris, Fernando Gonzalez, David M Hasan, Robert H Rosenwasser, Gary K Owens, Walter J Koch, Aaron S Dumont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:http://europepmc.org/articles/PMC3743809?pdf=render