Genotype Load Modulates Amyloid Burden and Anxiety-Like Patterns in Male 3xTg-AD Survivors despite Similar Neuro-Immunoendocrine, Synaptic and Cognitive Impairments

The wide heterogeneity and complexity of Alzheimer’s disease (AD) patients’ clinical profiles and increased mortality highlight the relevance of personalized-based interventions and the need for end-of-life/survival predictors. At the translational level, studying genetic and age interactions in a c...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Aida Muntsant, Lydia Giménez-Llort
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Subjects:
Alzheimer’s disease
genetic load
survival
end-of-life
frailty
heterogeneity
Online Access:https://www.mdpi.com/2227-9059/9/7/715

Internet

https://www.mdpi.com/2227-9059/9/7/715

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