Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues

Abstract Background Induced pluripotent stem cells (iPS) can be generated from various somatic cells and can subsequently be differentiated to multiple cell types of the body. This makes them highly promising for cellular therapy in regenerative medicine. However, to facilitate their clinical use an...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Hassan R. W. Ali, Salwa Suliman, Tarig Al-Hadi Osman, Manuel Carrasco, Ove Bruland, Daniela-Elena Costea, Helge Ræder, Kamal Mustafa
Format:	Article
Language:	English
Published:	BMC 2023-08-01
Subjects:	Platelet lysate Fetal bovine serum Fibroblasts Xenogenic Pluripotency
Online Access:	https://doi.org/10.1186/s13287-023-03403-7