Abnormal transcriptome-wide DNA demethylation induced by folate deficiency causes neural tube defects

Neural tube defect (NTDs) is one of the most common and serious fetal and neonatal birth defects. Neural tube closure (NTC) is an exquisitely coordinated process and this procedure is influenced by both genetic and environmental factor. Folic acid (FA) supplementation is an effective for prevention...

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書誌詳細

出版年:	Frontiers in Genetics
主要な著者:	Shan Wang, Yubing Zeng, Pei Pei, Xuejia He, Fan Liu, Ting Zhang
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2022-09-01
主題:	DNA demethylation DNA methylation folate neural tube defect H3K27ac
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fgene.2022.987210/full