Circadian Genes as Exploratory Biomarkers in DMD: Results From Both the mdx Mouse Model and Patients

Duchenne muscular dystrophy (DMD) is a rare genetic disease due to dystrophin gene mutations which cause progressive weakness and muscle wasting. Circadian rhythm coordinates biological processes with the 24-h cycle and it plays a key role in maintaining muscle functions, both in animal models and i...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Rachele Rossi, Maria Sofia Falzarano, Hana Osman, Annarita Armaroli, Chiara Scotton, Paola Mantuano, Brigida Boccanegra, Ornella Cappellari, Elena Schwartz, Anton Yuryev, Eugenio Mercuri, Enrico Bertini, Adele D’Amico, Marina Mora, Camilla Johansson, Cristina Al-Khalili Szigyarto, Annamaria De Luca, Alessandra Ferlini
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Subjects:	circadian rhythm Duchenne muscular dystrophy (DMD) mdx mice skeletal muscle RNA analysis biomarker
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2021.678974/full