A Suitable Membrane Distance Regulated by the RBD_ACE2 Interaction is Critical for SARS‐CoV‐2 Spike‐Mediated Viral Invasion

Abstract The receptor‐binding domain (RBD) of spike recognizing the receptor angiotensin‐converting enzyme 2 (ACE2) initiates membrane fusion between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and cell membrane. Although the structure of the RBD_ACE2 complex has been well studied,...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Mengdan Wu, Wei Li, Sheng Lin, Jiaqi Fan, Lele Cui, Yijuan Xiang, Kaiyu Li, Linwei Tang, Yanping Duan, Zimin Chen, Fanli Yang, Weiwei Shui, Guangwen Lu, Ying Lai
Format:	Article
Language:	English
Published:	Wiley 2023-10-01
Subjects:	membrane fusion RBD_ACE2 interaction SARS‐CoV‐2 spike
Online Access:	https://doi.org/10.1002/advs.202301478