Synthesis of branched and linear galactooligosaccharides related to glucuronoxylomannogalactan of Cryptococcus neoformans

This study focuses on the synthesis of a series of oligo-α-(1→6)-D-galactopyranosides bearing β-D-galactofuranosyl residues at O-2 and/or O-3, which relate structurally to fragments of glucuronoxylomannogalactan (GXMGal) from the fungal pathogen Cryptococcus neoformans that causes severe diseases in...

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Bibliographic Details

Published in:	Frontiers in Chemistry
Main Authors:	Vera S. Dorokhova, Bozhena S. Komarova, José O. Previato, Lúcia Mendonça Previato, Vadim B. Krylov, Nikolay E. Nifantiev
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Subjects:	Cryptococcus neoformans oligosaccharides glucuronoxylomannogalactan stereoselective glycosylation orthogonal protecting groups
Online Access:	https://www.frontiersin.org/articles/10.3389/fchem.2024.1501766/full