Cannabidiol interacts with the FXR/Nrf2 pathway and changes the CB1/CB2 receptors ratio in gentamicin-induced kidney injury in rats

Objective(s): Gentamicin-induced nephrotoxicity was used as an experimental model of kidney disease. The present study was performed to assess the therapeutic role of cannabidiol (CBD) against gentamicin-induced renal damage. Materials and Methods: Forty two male Wistar rats were randomly allocated...

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Bibliographic Details

Published in:	Iranian Journal of Basic Medical Sciences
Main Authors:	Vahideh Hokmabady, Azadeh Khalili, Seyed Ali Hashemi, Keshvad Hedayatyanfard, Soraya Parvari, Saeed Changizi-Ashtiyani, Gholamreza Bayat
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2023-03-01
Subjects:	cannabidiol cb1 receptors cb2 receptors farnesoid receptors gentamicin nrf2
Online Access:	https://ijbms.mums.ac.ir/article_21730_b7f3c020069c056230b385fd0451ff79.pdf