Acute lung injury induced by recombinant SARS-CoV-2 spike protein subunit S1 in mice

Abstract Background The intricacies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing acute lung injury (ALI) and modulating inflammatory factor dynamics in vivo remain poorly elucidated. The present study endeavors to explore the impact of the recombinant SARS-CoV-2 spike prot...

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Bibliographic Details

Published in:	Respiratory Research
Main Authors:	Jiwei Zhu, Jinglin Wu, Manlu Lu, Qianqian Jiao, Xiaojing Liu, Lu Liu, Mingzhen Li, Bin Zhang, Junhong Yan, Yan Yu, Lei Pan
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Subjects:	COVID-19 SARS-CoV-2 Acute lung injury Spike protein
Online Access:	https://doi.org/10.1186/s12931-025-03143-7