Preclinical Insights into the Role of Kir4.1 in Chronic Pain and Depression: Mechanisms and Therapeutic Potential

Chronic pain and mental health disorders, such as depression and anxiety, frequently co-occur and share underlying mechanisms involving neuronal excitability and synaptic transmission. The inwardly rectifying potassium channel 4.1 (Kir4.1), predominantly expressed in glial cells, is crucial for main...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Tingfeng Zha, Xinyi Fang, Jiamin Wan, Xiaoyan Chen, Jiu Lin, Qianming Chen
Format:	Article
Language:	English
Published:	MDPI AG 2025-01-01
Subjects:	the inwardly rectifying potassium channel 4.1 pain mental health disorders glial cells comorbidity preclinical studies
Online Access:	https://www.mdpi.com/2218-273X/15/2/165