Accumulation of Arsenic Speciation and In Vivo Toxicity Following Oral Administration of a Chinese Patent Medicine Xiao-Er-Zhi-Bao-Wan in Rats

Realgar-containing traditional Chinese medicines such as Xiao-Er-Zhi-Bao-Wan (XEZBW), have been widely used for thousands of years. However, events associated with arsenic-induced ailments have increasingly become a public concern. To address the toxicity of XEZBW, we studied the histopathology and...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Jiaoyang Luo, Xu Han, Xiaowen Dou, Lei Zhang, Shihai Yang, Meihua Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-07-01
Subjects:	Xiao-Er-Zhi-Bao-Wan arsenic speciation toxicity histopathology blood biochemistry
Online Access:	http://journal.frontiersin.org/article/10.3389/fphar.2017.00491/full