Better treatment outcomes with aripiprazole long-acting injection in community and incarcerated patients with serious mental illness

ImportanceAripiprazole, a partial D2 receptor agonist, is proposed to enhance prefrontal cortex (PFC) dopamine function, improving working memory and GABA transmission, which supports social functioning. Long-acting injectable (LAI) antipsychotics are known to improve patient adherence, leading to e...

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Bibliographic Details

Published in:	Frontiers in Psychiatry
Main Authors:	Erasmia I. Koiliari, Ioannis Mouzas, Georgios Alevizopoulos, Otto Lesch, Henriette Walter, Emmanouil L. Pasparakis
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	aripiprazole long -acting treatment serious mental illness (SMI) psychosis quality of life hospitalizations
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1499400/full