Inhibiting sphingosine 1-phosphate lyase: From efficacy to mechanism

Sphingosine-1 phosphate (S1P) is a lipid metabolite regulating diverse biological processes, including proliferation, differentiation, migration, and apoptosis, highlighting its physiological and therapeutic significance. Current S1P-based therapeutic approaches primarily focus on modulating the dow...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Nelson George, Junhua Xiao
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	Sphingosine 1 phosphate S1P Sphingosine 1 phosphate lyase SPL Inhibitor Glial cells
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996124001852