The alarmin tandem: unraveling the complex effect of S100A8/A9 – from atherosclerosis to cardiac arrhythmias

IntroductionInflammation plays a crucial role in the pathophysiology of cardiovascular diseases (CVDs), particularly in heart failure (HF), cardiac arrhythmias, and atherosclerotic cardiovascular disease (ASCVD). The calcium-binding proteins S100A8 and S100A9, primarily functioning as a heterodimer...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Dan-Alexandru Cozac, Vasile-Bogdan Halațiu, Alina Scridon
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Subjects:
arrhythmias
atherosclerosis
inflammation
S100A8/A9
heart failure
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1630410/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1630410/full

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