Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis

Abstract Background Obesity and the forkhead box O1(FOXO1) affect the survival of breast cancer patients, but the underlying mechanism remains unclear. We aimed to investigate the role of FOXO1 in obesity-associated-breast cancer. Methods We screened 383 breast disease patients from the first affili...

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发表在:	Cancer Cell International
Main Authors:	Xiu Chen, Heda Zhang, Zheng Fang, Dandan Wang, Yuxin Song, Qian Zhang, Junchen Hou, Sujin Yang, Di Xu, Yinjiao Fei, Wei Zhang, Jian Zhang, Jinhai Tang, Lei Li
格式:	文件
语言:	英语
出版:	BMC 2024-08-01
主题:	Breast cancer Adipocyte FOXO1 Metastasis Copper homeostasis
在线阅读:	https://doi.org/10.1186/s12935-024-03433-y