MmuPV1-Induced Cutaneous Squamous Cell Carcinoma Arises Preferentially from Lgr5+ Epithelial Progenitor Cells

Murine papillomavirus, MmuPV1, causes natural infections in laboratory mice that can progress to squamous cell carcinoma (SCC) making it a useful preclinical model to study the role of papillomaviruses in cancer. Papillomavirus can infect cells within hair follicles, which contain multiple epithelia...

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Bibliographic Details
Published in:Viruses
Main Authors: Ruben Moreno, Darya Buehler, Paul F. Lambert
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Subjects:
Lgr5
mouse papillomavirus
cell of origin
Online Access:https://www.mdpi.com/1999-4915/14/8/1751

Internet

https://www.mdpi.com/1999-4915/14/8/1751

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