The CK1ε/SIAH1 axis regulates AXIN1 stability in colorectal cancer cells

Casein kinase 1ε (CK1ε) and axis inhibitor 1 (AXIN1) are crucial components of the β‐catenin destruction complex in canonical Wnt signaling. CK1ε has been shown to interact with AXIN1, but its physiological function and role in tumorigenesis remain unknown. In this study, we found that CK1δ/ε inhibi...

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出版年:	Molecular Oncology
主要な著者:	Mengfang Yan, Zijie Su, Xiaoyi Pang, Hanbin Wang, Han Dai, Jiong Ning, Shanshan Liu, Qi Sun, Jiaxing Song, Xibao Zhao, Desheng Lu
フォーマット:	論文
言語:	英語
出版事項:	Wiley 2024-09-01
主題:	AXIN1 CK1ε colorectal cancer SIAH1 ubiquitination Wnt/β‐catenin
オンライン･アクセス:	https://doi.org/10.1002/1878-0261.13624