SAFETY AND IMMUNOGENICITY OF COLD-ADAPTED RECOMBINANT INFLUENZA VECTOR EXPRESSING ESAT-6 AND AG85А ANTIGENS OF M. TUBERCULOSIS

Recombinant viral vectors represent one of the most promising platforms for creating a new generation of vaccines against tuberculosis. We constructed a vaccine candidate based on a cold-adapted influenza vector with a truncated NS1 protein containing an insert of tuberculosis ESAT-6 and Ag85A antig...

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Bibliographic Details

Published in:	Вопросы вирусологии
Main Authors:	M. V. Sergeeva, A. A. Pulkina, K. A. Vasiliev, E. A. Romanovskaya-Romanko, A. B. Komissarov, O. A. Kuchur, A. Yu. Egorov, L. M. Tsybalova, M. A. Stukova
Format:	Article
Language:	English
Published:	Central Research Institute for Epidemiology 2017-12-01
Subjects:	vectored vaccine m. tuberculosis antigen influenza ns1 protein cold-adapted influenza vector recombinant virus
Online Access:	https://virusjour.crie.ru/jour/article/viewFile/174/84