Identification of Zirconia Particle Uptake in Human Osteoblasts by ToF-SIMS Analysis and Particle-Size Effects on Cell Metabolism

As the use of zirconia-based nano-ceramics is rising in dentistry, the examination of possible biological effects caused by released nanoparticles on oral target tissues, such as bone, is gaining importance. The aim of this investigation was to identify a possible internalization of differently size...

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Bibliographic Details

Published in:	Nanomaterials
Main Authors:	Alexander Welle, Kerstin Rabel, Matthias Schwotzer, Ralf Joachim Kohal, Thorsten Steinberg, Brigitte Altmann
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	zirconia nano/microparticles Time-of-Flight Secondary Ion Mass Spectrometry human alveolar bone alamarBlue assay
Online Access:	https://www.mdpi.com/2079-4991/12/23/4272