Mycobacterium tuberculosis specific protein Rv1509 modulates osteoblast and osteoclast differentiation via TLR2 signaling

Summary: Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), is one of the most ancient diseases recorded. In cases of bone TB, it significantly disrupts bone homeostasis, though the precise mechanisms are poorly understood and effective treatment targets are scarce. Our study investigat...

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Bibliographic Details

Published in:	iScience
Main Authors:	Pan Liu, Jiezhong Deng, Yusheng Yang, Wenxi Bai, Shengtao Dong, Zehua Zhang
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	natural sciences biological sciences biochemistry physiology immunology microbiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004225003670