Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours

Abstract Despite the current wealth of sequencing data, one‐third of all biochemically characterized metabolic enzymes lack a corresponding gene or protein sequence, and as such can be considered orphan enzymes. They represent a major gap between our molecular and biochemical knowledge, and conseque...

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Bibliographic Details

Published in:	Molecular Systems Biology
Main Authors:	Takuji Yamada, Alison S Waller, Jeroen Raes, Aleksej Zelezniak, Nadia Perchat, Alain Perret, Marcel Salanoubat, Kiran R Patil, Jean Weissenbach, Peer Bork
Format:	Article
Language:	English
Published:	Springer Nature 2012-05-01
Subjects:	genomics metabolic pathways metagenomics neighbourhood information orphan enzymes
Online Access:	https://doi.org/10.1038/msb.2012.13