Influence of CD16 (FcγRIII) Expression on Peripheral Blood Mononuclear Cells on Response to Treatment with Rituximab in Pemphigus: A Cross-Sectional Study

Background: Rituximab-mediated B-cell depletion in pemphigus patients is majorly caused by antibody-dependent cellular cytotoxicity. This is mediated by Fcγ receptors on immune cells, particularly FcγRIIIa (CD16) on natural killer (NK) cells. This study investigates the impact of FcγRIII expression...

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Bibliographic Details

Published in:	Indian Dermatology Online Journal
Main Authors:	Ankur Sharma, Anshika Chauhan, Hitaishi Mehta, Sanjeev Handa, Naresh Sachdeva, Rahul Mahajan, Arnab Pal, Dipankar De
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-07-01
Subjects:	cd16 expression fcγ receptors fcγriiia (cd16) fcγriiia genotypes fcγriiia-158v/f polymorphism monocytes nk cells nk-t cells pemphigus rituximab remission
Online Access:	https://journals.lww.com/10.4103/idoj.idoj_891_24