Turnover number predictions for kinetically uncharacterized enzymes using machine and deep learning

Abstract The turnover number k cat, a measure of enzyme efficiency, is central to understanding cellular physiology and resource allocation. As experimental k cat estimates are unavailable for the vast majority of enzymatic reactions, the development of accurate computational prediction methods is h...

詳細記述

書誌詳細
出版年:Nature Communications
主要な著者: Alexander Kroll, Yvan Rousset, Xiao-Pan Hu, Nina A. Liebrand, Martin J. Lercher
フォーマット: 論文
言語:英語
出版事項: Nature Portfolio 2023-07-01
オンライン・アクセス:https://doi.org/10.1038/s41467-023-39840-4