Use of factorial design in formulation and evaluation of intrarectal in situ gel of sumatriptan

The study's goal was to create an in situ intrarectal mucoadhesive gel of sumatriptan (SMT) combining mucoadhesive polymer (xyloglucan) and thermosensitive polymers (poloxamer 407 and poloxamer 188) to prolong rectal residence time for treatment of migraines. Nine SMT mucoadhesive rectal in sit...

Full description

Bibliographic Details

Published in:	Journal of Advanced Pharmaceutical Technology & Research
Main Authors:	Hanan J Kassab, Hussein K Alkufi, Lina S Hussein
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2023-01-01
Subjects:	cold method in situ gels poloxamer 188 poloxamer 407 sumatriptan xyloglucan
Online Access:	http://www.japtr.org/article.asp?issn=2231-4040;year=2023;volume=14;issue=2;spage=119;epage=124;aulast=Kassab