Flavopiridol induces cell cycle arrest and apoptosis by interfering with CDK1 signaling pathway in human ovarian granulosa cells

Abstract Several clinical trials have been conducted to evaluate the use of flavopiridol (FP) to treat a variety of cancers, and almost all cancer drugs were found to be associated with toxicity and side effects. It is not clear whether the use of FP will affect the female reproductive system. Granu...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:Scientific Reports
المؤلفون الرئيسيون: Xiao-Zhen Li, Wei Song, Zheng-Hui Zhao, You-Hui Lu, Gen-Lu Xu, Li-Jia Yang, Shen Yin, Qing-Yuan Sun, Lei-Ning Chen
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2024-10-01
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1038/s41598-024-77032-2