Acrylamide Induces Antiapoptotic Autophagy and Apoptosis by Activating PERK Pathway in SH-SY5Y Cells

Acrylamide (ACR) is a commonly used organic compound that exhibits evident neurotoxicity in humans. Our previous studies showed that the mechanisms of ACR-caused neurotoxicity included apoptosis, PERK-mediated endoplasmic reticulum stress, and autophagy, but the relationships among them were still u...

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Bibliographic Details

Published in:	Toxics
Main Authors:	Yiqi Wang, Ying Liu, Xing Zhang, Yang Jiao, Lian Duan, Ruijie Cheng, Ning Yang, Hong Yan
Format:	Article
Language:	English
Published:	MDPI AG 2025-01-01
Subjects:	acrylamide PERK pathway apoptosis autophagy
Online Access:	https://www.mdpi.com/2305-6304/13/1/41