An exosomal strategy for targeting cancer-associated fibroblasts mediated tumors desmoplastic microenvironments

Abstract Tumors desmoplastic microenvironments are characterized by abundant stromal cells and extracellular matrix (ECM) deposition. Cancer-associated fibroblasts (CAFs), as the most abundant of all stromal cells, play significant role in mediating microenvironments, which not only remodel ECM to e...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Xiaoxia Xue, Xiangpeng Wang, Mingshi Pang, Liuchunyang Yu, Jinxiu Qian, Xiaoyu Li, Meng Tian, Cheng Lu, Cheng Xiao, Yuanyan Liu
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Subjects:	Desmoplastic tumors Cancer-associated fibroblasts Engineered exosomes Drug delivery Theranostic
Online Access:	https://doi.org/10.1186/s12951-024-02452-1