AURKB promotes bladder cancer progression by deregulating the p53 DNA damage response pathway via MAD2L2

Abstract Background Bladder cancer (BC) is the most common urinary tract malignancy. Aurora kinase B (AURKB), a component of the chromosomal passenger protein complex, affects chromosomal segregation during cell division. Mitotic arrest-deficient 2-like protein 2 (MAD2L2) interacts with various prot...

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Bibliographic Details
Published in:Journal of Translational Medicine
Main Authors: Linzhi Li, Pengcheng Jiang, Weimin Hu, Fan Zou, Ming Li, Ting Rao, Yuan Ruan, Weimin Yu, Jinzhuo Ning, Fan Cheng
Format: Article
Language:English
Published: BMC 2024-03-01
Subjects:
Bladder cancer
Aurora kinase B
Mitotic arrest-deficient 2-like protein 2
p53
Online Access:https://doi.org/10.1186/s12967-024-05099-6

Internet

https://doi.org/10.1186/s12967-024-05099-6

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