Novel <i>N</i>-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

Although opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common drugs used in persistent pain treatment; they have shown many side effects. The development of new analgesics endowed with mu opioid receptor/delta opioid receptor (MOR/DOR) activity represents a promising alterna...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Rita Turnaturi, Santina Chiechio, Lorella Pasquinucci, Salvatore Spoto, Giuliana Costanzo, Maria Dichiara, Silvia Piana, Margherita Grasso, Emanuele Amata, Agostino Marrazzo, Carmela Parenti
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Subjects:	multitarget drugs MOR/DOR agonists PRE-084 formalin test
Online Access:	https://www.mdpi.com/1420-3049/27/16/5135