PEG-Free Polyion Complex Nanocarriers for Brain-Derived Neurotrophic Factor

Many therapeutic formulations incorporate poly(ethylene glycol) (PEG) as a stealth component to minimize early clearance. However, PEG is immunogenic and susceptible to accelerated clearance after multiple administrations. Here, we present two novel reformulations of a polyion complex (PIC), origina...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Pharmaceutics
المؤلفون الرئيسيون:	James M. Fay, Chaemin Lim, Anna Finkelstein, Elena V. Batrakova, Alexander V. Kabanov
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2022-06-01
الموضوعات:	poly(ethylene glycol) poly(2-oxazoline) polyion complex nanoformulation brain-derived neurotrophic factor microfluidic mixing
الوصول للمادة أونلاين:	https://www.mdpi.com/1999-4923/14/7/1391