Competing ParA structures space bacterial plasmids equally over the nucleoid.

Low copy number plasmids in bacteria require segregation for stable inheritance through cell division. This is often achieved by a parABC locus, comprising an ATPase ParA, DNA-binding protein ParB and a parC region, encoding ParB-binding sites. These minimal components space plasmids equally over th...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Robert Ietswaart, Florian Szardenings, Kenn Gerdes, Martin Howard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004009&type=printable