The role of plasma metagenomic sequencing in identification of Balamuthia mandrillaris encephalitis

Abstract Balamuthia mandrillaris is a rare, free-living amoeba (FLA) that causes granulomatous amoebic encephalitis, a disease with close to 90% mortality. The geographical ranges of many FLA are expanding, potentially increasing human exposure to B. mandrillaris. Here, we report a case of a 58-year...

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Bibliographic Details

Published in:	Acta Neuropathologica Communications
Main Authors:	Sarah Y. Edminster, Ryan W. Rebbe, Christopher Khatchadourian, Kyle M. Hurth, Anna J. Mathew, Julie Huss-Bawab, Mark S. Shiroishi, Devin Clark, Andrew P. Norgan, Susan M. Butler-Wu, Annie Hiniker
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Balamuthia Balamuthia mandrillaris Amoeba Amoebic encephalitis Plasma metagenomic sequencing Free living amoeba
Online Access:	https://doi.org/10.1186/s40478-025-01963-8