Sexual Dimorphism of Synaptic Plasticity Changes in CA1 Hippocampal Networks in Hypergravity-Exposed Mice—New Insights for Cognition in Space

Background: We recently reported sex-dependent impairment in cognitive functions in male and female mice exposed for 24 h, 48 h or 15 days to 2G hypergravity (HG). Methods: In the present study, we investigated brain functional correlates by analyzing synaptic activity and plasticity in the CA1 area...

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Bibliographic Details

Published in:	Cells
Main Authors:	Mathilde Wullen, Valentine Bouet, Thomas Freret, Jean-Marie Billard
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Subjects:	hypergravity electrophysiology long term potentiation NMDA receptor long term depression memory
Online Access:	https://www.mdpi.com/2073-4409/14/15/1186