Eph-ephrin signaling couples endothelial cell sorting and arterial specification

Abstract Cell segregation allows the compartmentalization of cells with similar fates during morphogenesis, which can be enhanced by cell fate plasticity in response to local molecular and biomechanical cues. Endothelial tip cells in the growing retina, which lead vessel sprouts, give rise to arteri...

Full description

Bibliographic Details
Published in:Nature Communications
Main Authors: Jonas Stewen, Kai Kruse, Anca T. Godoi-Filip, Zenia, Hyun-Woo Jeong, Susanne Adams, Frank Berkenfeld, Martin Stehling, Kristy Red-Horse, Ralf H. Adams, Mara E. Pitulescu
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Online Access:https://doi.org/10.1038/s41467-024-46300-0