The role of s-palmitoylation in neurological diseases: implication for zDHHC family

S-palmitoylation is a reversible posttranslational modification, and the palmitoylation reaction in human-derived cells is mediated by the zDHHC family, which is composed of S-acyltransferase enzymes that possess the DHHC (Asp-His-His-Cys) structural domain. zDHHC proteins form an autoacylation inte...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Dan Liao, Yutao Huang, Dan Liu, Haofuzi Zhang, Xinyu Shi, Xin Li, Peng Luo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	S-palmitoylation protein acyltransferase zDHHC glutamate receptor scaffold protein neurological diseases
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1342830/full