Evidence of apoptosis as an early event leading to cyclophosphamide-induced primordial follicle depletion in a prepubertal mouse model

IntroductionThe mechanisms leading to ovarian primordial follicle depletion following gonadotoxic chemotherapy with cyclophosphamide and other cytotoxic drugs are currently understood through two main explanatory theories: apoptosis and over-activation. Discrepancies between the findings of differen...

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書誌詳細

出版年:	Frontiers in Endocrinology
主要な著者:	Xia Hao, Arturo Reyes Palomares, Amandine Anastácio, Kui Liu, Kenny A. Rodriguez-Wallberg
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2024-10-01
主題:	ovary primordial follicle growing follicle cyclophosphamide apoptosis overactivation
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1322592/full