Age-related decline in spermatogenic activity accompanied with endothelial cell senescence in male mice

Summary: Male fertility decreases with aging, with spermatogenic decline being one of its causes. Altered testis environment is suggested as a cause of the phenotype; however, the associated mechanisms remain unclear. Herein, we investigated the age-related changes in testicular somatic cells on spe...

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Bibliographic Details

Published in:	iScience
Main Authors:	Manabu Ozawa, Hideto Mori, Tsutomu Endo, Yu Ishikawa-Yamauchi, Daisuke Motooka, Chihiro Emori, Masahiro Ikawa
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Subjects:	biological sciences Physiology cell biology Transcriptomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223025336