Elevated Cellular Uptake of Succinimide- and Glucose-Modified Liposomes for Blood–Brain Barrier Transfer and Glioblastoma Therapy

The uptake of four liposomal formulations was tested with the murine endothelial cell line bEnd.3 and the human glioblastoma cell line U-87 MG. All formulations were composed of DPPC, cholesterol, 5 mol% of mPEG (2000 Da, conjugated to DSPE), and the dye DiD. Three of the formulations had an additio...

Full description

Bibliographic Details

Published in:	Biomedicines
Main Authors:	Larissa J. Lubitz, Moritz P. Haffner, Harden Rieger, Gero Leneweit
Format:	Article
Language:	English
Published:	MDPI AG 2024-09-01
Subjects:	glucose drug targeting liposomes blood–brain barrier glioblastoma
Online Access:	https://www.mdpi.com/2227-9059/12/9/2135