The Emerging Roles of Rad51 in Cancer and Its Potential as a Therapeutic Target

Defects in DNA repair pathways are emerging hallmarks of cancer. Accurate DNA repairs and replications are essential for genomic stability. Cancer cells require residual DNA repair capabilities to repair the damage from replication stress and genotoxic anti-tumor agents. Defective DNA repair also pr...

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Bibliographic Details
Published in:Frontiers in Oncology
Main Authors: Ziyi Wang, Renxiang Jia, Linlin Wang, Qiwei Yang, Xiaohai Hu, Qiang Fu, Xinyu Zhang, Wenya Li, Yi Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Subjects:
DNA repair
PARP inhibitor
Rad51
therapy resistance
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.935593/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.935593/full

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