Unbalanced production of LTB4/PGE2 driven by diabetes increases susceptibility to cutaneous leishmaniasis

Poorly controlled diabetes mellitus leads to several comorbidities, including susceptibility to infections. Hyperglycemia increases phagocyte responsiveness, however immune cells from people with diabetes show inadequate antimicrobial functions. We and others have shown that aberrant production of l...

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Bibliographic Details

Published in:	Emerging Microbes and Infections
Main Authors:	Icaro Bonyek-Silva, Sara Nunes, Reinan L. Santos, Filipe R. Lima, Alexsandro Lago, Juliana Silva, Lucas P. Carvalho, Sergio M. Arruda, Henrique C. Serezani, Edgar M. Carvalho, Claudia I. Brodskyn, Natalia M. Tavares
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-01-01
Subjects:	Diabetes human leishmaniasis Leishmania braziliensis lipid mediators LTB4 PGE2
Online Access:	https://www.tandfonline.com/doi/10.1080/22221751.2020.1773744