Titanium alloy surface modification with polyphenolic layer and zinc ions for sustained trimethoprim delivery: A coordination-mediated antibiotic immobilization approach

Titanium-based implants are commonly applied in orthopedic and dental treatments, yet their durability is limited by issues such as bacterial adhesion and the mechanical mismatch between the implant and natural bone. In this work the surface modification of titanium implants was investigated by deve...

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Bibliographic Details

Published in:	Materials & Design
Main Authors:	Marcel Jakubowski, Aleksandra Domke, Monika Zielińska, Maria Ratajczak, Łukasz Ławniczak, Adam Voelkel, Marta Trzaskowska, Vladyslav Vivcharenko, Agata Przekora, Mariusz Sandomierski
Format:	Article
Language:	English
Published:	Elsevier 2025-10-01
Subjects:	Titanium implants Surface modification Polyphenols Trimethoprim
Online Access:	http://www.sciencedirect.com/science/article/pii/S0264127525011463