Systematic Review of Gossypol/AT-101 in Cancer Clinical Trials

The potential of gossypol and of its R-(−)-enantiomer (R-(−)-gossypol acetic acid, AT-101), has been evaluated for treatment of cancer as an independent agent and in combination with standard chemo-radiation-therapies, respectively. This review assesses the evidence for safety and clinical effective...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Olga Renner, Mascha Mayer, Christian Leischner, Markus Burkard, Alexander Berger, Ulrich M. Lauer, Sascha Venturelli, Stephan C. Bischoff
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	oral gossypol AT-101 clinical trial cancer oncologic patients
Online Access:	https://www.mdpi.com/1424-8247/15/2/144