Tregopathy in focus

Primary immune regulatory disorders are a newly coined term for a group of disorders in which autoimmune complications predominate. Herein, we present a case series of 26 patients with various regulatory T-cell (Treg) pathway defects who presented with multiple autoimmune complications. Twenty-six p...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Vaishnavi Venkatachari Iyengar, Vijaya Gowri, Akshaya Sanjay Chougule, Prasad Taur, Manisha Rajan Madkaikar, Minnie Bodhanwala, Mukesh Manharlal Desai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-10-01
Subjects:
Treg - regulatory T cell
autoimmune disease
polyautoimmunity
LRBA and CTLA-4 deficiencies
JAK- STAT signaling pathway
immune dysregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1658140/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1658140/full

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