Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis

Individuals with chronic kidney disease (CKD) exhibit a significantly elevated risk of premature mortality, predominantly attributable to cardiovascular etiologies. Atherosclerosis is a multifactorial vascular pathology driven by dysregulated lipid metabolism. Notably, patients with CKD exhibit an a...

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Bibliographic Details

Published in:	Renal Failure
Main Authors:	Jianan Feng, Ruike Chen, Yao Chen, Jie Deng, Jiali Wei
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Uremia accelerated atherosclerosis vascular smooth muscle cell autophagy PI3K/PKB signal pathway
Online Access:	https://www.tandfonline.com/doi/10.1080/0886022X.2025.2538268