Screening and preclinical assessment of novel Mycobacterium tuberculosis recombinant antigens based tuberculin skin testing

IntroductionA new class of Mycobacterium tuberculosis (MTB) antigen-based skin tests was recommended by WHO for the diagnosis of TB infection. However, their performance in some settings remains suboptimal. Our study focused on screening novel MTB recombinant antigens for skin tests and evaluating t...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Xichao Ou, Eryong Liu, Faiqa Rashid, Shaojun Pei, Guoqin Zhang, Richard Anthony, Ruida Xing, Fei Huang, Hui Xia, Yang Zheng, Yuanyuan Song, Yang Zhou, Bing Zhao, Shengfen Wang, Minggui Lin, Lin Zhou, Yanlin Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	MTB recombinant antigens tuberculin skin test screening preclinical efficacy EM
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1498448/full