Neuroprotection by Endoplasmic Reticulum Stress-Induced HRD1 and Chaperones: Possible Therapeutic Targets for Alzheimer’s and Parkinson’s Disease

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are neurodegenerative disorders with a severe medical and social impact. Further insights from clinical and scientific studies are essential to develop effective therapies. Various stresses on the endoplasmic reticulum (ER) cause unfolded/misfold...

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Bibliographic Details

Published in:	Medical Sciences
Main Authors:	Jun Nomura, Toru Hosoi, Masayuki Kaneko, Koichiro Ozawa, Akinori Nishi, Yasuyuki Nomura
Format:	Article
Language:	English
Published:	MDPI AG 2016-08-01
Subjects:	endoplasmic reticulum unfolded protein responses HRD1 molecular chaperone degradation/refolding of misfolded proteins Alzheimer’s disease Parkinson’s disease therapeutic development
Online Access:	http://www.mdpi.com/2076-3271/4/3/14