Long-Term Persistence of Mitochondrial DNA Instability in HIV-Exposed Uninfected Children during and after Exposure to Antiretroviral Drugs and HIV

HIV-exposed uninfected (HEU) children show impaired health outcomes during childhood. A high rate of mitochondrial DNA (mtDNA) instability was reported in the blood of HEU at birth. We aimed to explore the relationship between these health outcomes and mtDNA deletions over time in a case series of 2...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Valérie Desquiret-Dumas, Morgana D’Ottavi, Audrey Monnin, David Goudenège, Nicolas Méda, Amélie Vizeneux, Chipepo Kankasa, Thorkild Tylleskar, Céline Bris, Vincent Procaccio, Nicolas Nagot, Philippe Van de Perre, Pascal Reynier, Jean-Pierre Molès
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Subjects:	HIV neonates mitochondria clinical outcomes neurodevelopment genetic alterations
Online Access:	https://www.mdpi.com/2227-9059/10/8/1786