Pharmacokinetic study of Strongylocentrotus nudus egg polysaccharide in rats and beagles using a 3H-labeling method

Strongylocentrotus nudus egg polysaccharide (SEP) extracted from sea urchins has potential anticancer activity. However, little is known about its pharmacokinetic properties. To investigate the pharmacokinetics of SEP, it was radiolabeled with tritium. Furthermore, a sensitive, selective, and rapid...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Han Xing, Xiaojie Zhu, Jianmin Liao, Ying Kong, Yayuan Lu, Di Zhao, Ning Li, Xijing Chen, Zhiying Qin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	Strongylocentrotus nudus egg polysaccharide 3H-labeling method pharmacokinetics tritium beagles rats
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1109084/full