Chemically Synthesized <i>Alcaligenes</i> Lipid A Shows a Potent and Safe Nasal Vaccine Adjuvant Activity for the Induction of <i>Streptococcus</i> <i>pneumoniae</i>-Specific IgA and Th17 Mediated Protective Immunity

Effective and safe vaccine adjuvants are needed to appropriately augment mucosal vaccine effects. Our previous study demonstrated that lipopolysaccharide (LPS) from Peyer’s patch resident <i>Alcaligenes</i> stimulated dendritic cells to promote the production of mucosal immunity-enhancin...

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書誌詳細

出版年:	Microorganisms
主要な著者:	Ken Yoshii, Koji Hosomi, Atsushi Shimoyama, Yunru Wang, Haruki Yamaura, Takahiro Nagatake, Hidehiko Suzuki, Huangwenxian Lan, Hiroshi Kiyono, Koichi Fukase, Jun Kunisawa
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2020-07-01
主題:	<i>Alcaligenes</i> lipid A IgA antibody neutrophil pneumococcal surface protein A (PspA), <i>Streptococcus pneumoniae</i> Th17 response
オンライン･アクセス:	https://www.mdpi.com/2076-2607/8/8/1102